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of the gene known as GTPase of immunity-a

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WELLINGTON, Jan. 13 (Xinhua) -- New Zealand Customs officers have arrested three young foreign nationals after finding illegal drugs with a street value of 5 million NZ dollars (3.56 million U.S. dollars) in false-bottomed suitcases at Auckland Airport.


The three men -- all aged 24 -- were arrested on arrival from Singapore last week after x-rays led to the discovery of 12 kilograms MDMA (3,4-methylenedioxy-methamphetamine), commonly known as ecstasy crystals, hidden in the suitcases.


The find was made as Customs officers stepped up profiling of visitors and cooperation with other agencies during the peak travel season over th southern summer, Customs investigations manager Maurice O'Brien said in a statement Friday.


""Meth (methamphetamine) is still the main choice for drug couriers and like meth, New Zealand's price for MDMA is amongst the highest in the world, making us an attractive market for criminals,"" said O'Brien.


The three men -- whose nationalities were not disclosed -- were scheduled to reappear in court in Auckland on Jan. 27 on charges of importing an illegal drug.


They faced a maximum penalty of 14 years in prison.

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BEIJING Cheap Jimmy Graham Jersey , Jan. 31 (Xinhua) -- Stargazers across China looked up at the moon to witness the rare sight of a "super blue red Moon" Wednesday night.


In Beijing, the total lunar eclipse began at 8:51 p.m. when the moon entered the shadow of Earth and appeared to be wrapped in coppery blue.


As the moon passed into Earth's shadow, it exhibited a reddish tinge as the sunlight was refracted while shining through the Earth's atmosphere. The red moon graced the sky in most parts of China for over an hour, according to the Beijing Planetarium.


According to Zhang Yang, an expert at the Purple Mountain Observatory in Nanjing, capital of east China's Jiangsu Province, the second full moon in a month is a blue moon. On Wednesday, the moon also happened to be rather close and bright because its orbit was near its closest point to Earth, thus called a supermoon.


"Supermoons occur rather often, but we rarely see it sync up with a lunar eclipse, or blood moon," Zhang said.


On Wednesday night, the cosmic sight was seen in most parts of China where the weather was clear. The western parts of Tibet Autonomous Region and Xinjiang Uygur Autonomous Region may have missed the beginning of the lunar eclipse, according to Zhang.


Popular video sites provided live broadcasts of the "super blue red moon." People shared their "moon moments" on social media, and pictures of the lunar eclipse went viral on the Internet.


Over 1,000 people gathered at the Beijing Planetarium to use the equipments to watch the moon. Many parents brought their children for a lesson in science.


Wei Xiaofan, 37, is an ardent fan of astronomy. "I wouldn't miss each lunar eclipse, because each time the moon is in a different charm," he said.


"The sky is the most beautiful and most profound field where there is an immense amount to be learnt," said Hai Jintao, an expert in material science, at the planetarium.


Fans and astronomers also gathered at Lijiang observatory in Lijiang city in southwest China's Yunnan Province. "I'm here to observe the optical telescope here, because it is one of Asia's largest. It is a good place to take pictures of the moon tonight," said Masaoki Hagino, an expert in astronomy from Japan.


The Lijiang observatory is located at Gaomei village in Yulong Naxi Autonomous County.


Chinese folklore once interpreted the lunar eclipse as the moon being eaten up by a heavenly dog, and people would play drums and burn fireworks to drive the heavenly dog away.


LOS ANGELES, Jan. 30 (Xinhua) -- U.S. scientists have identified how a gene mutation affects T cell function to promote immune disorders and then tested a treatment based on the discovery--successfully fixing donated immune cells from a 16-year-old boy with an abnormally low level of white blood cells called lymphopenia.


Immune system disorders lead to abnormally low immune activity (deficiency) or overactivity (autoimmunity). Immune deficiency diseases decrease the body's ability to fight infection, while autoimmunity prompts the body to attack its own tissues. Both are common causes of illness, and malfunctioning T cells are linked to both.


The discovery, detailed in a paper published on Tuesday in Nature Communications, centers on mutation of the gene known as GTPase of immunity-associated protein 5 (Gimap5), which is important to the healthy formation and function of CD4+ T cells, one of the immune system's super soldiers against infection and disease.


The protein associated with the Gimap5 gene, also Gimap5, is important because it regulates a protein that inactivates an enzyme called GSK3, researchers at the Cincinnati Children say in a news release.


"Our data suggest GSK3 inhibitors will improve T cell survival and function and may prevent or correct immune-related disorders in people with Gimap5 loss-of-function mutations," Kasper Hoebe, PhD, Division of Immunobiology, was quoted as saying in a statement. "Therapeutically targeting this pathway may be relevant for treating people with Gimap5 mutations linked to autoimmunity in Type 1 diabetes, systemic lupus erythematosus or asthma."


According to the study, if GSK3 isn't inactivated it causes DNA damage in T cells that are expanding, causing the cells to not survive or function correctly.


The team, led by Hoebe, also identified a 16-year-old human patient with lymphopenia, who carried a rare, homozygous Gimap5 mutation that resulted in a complete lack of Gimap5 protein.


In mice and human blood cells, the researchers tested drugs that inhibit GSK3, improving immune system function in mice and restoring normal T cell function in the human cells.


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